Researchers Increase and Decrease Pain Sensitivity Using Light
Read the full article Researchers Increase and Decrease Pain Sensitivity Using Light at NeuroscienceNews.com.
The mice in Scott Delp’s lab, unlike their human counterparts, can get pain relief from the glow of a yellow light.
Right now these mice are helping scientists study pain — how and why it occurs, and why some people feel it so intensely without any obvious injury. But Delp, PhD, professor of bioengineering and of mechanical engineering, hopes one day the work he does with these mice could also help people who are in chronic, debilitating pain.
The research is in Nature Biotechnology. (full access paywall)
Research: “Virally mediated optogenetic excitation and inhibition of pain in freely moving nontransgenic mice” by Shrivats Mohan Iyer, Kate L Montgomery, Chris Towne, Soo Yeun Lee, Charu Ramakrishnan, Karl Deisseroth and Scott L Delp in Nature Biotechnology. doi:10.1038/nbt.2834
Image: A histological image demonstrating opsin transduction in unmyelinated axons. Credit Shrivats Iyer and Kate Montgomery/Stanford University.